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Revenues from the drug unit’s top products, blood thinner Xarelto and eye drug Eylea, will peak over the next six years. “That gives Bayer a window of one two three years to license something in and, if not, to show that something is yet to emerge from its earlier-stage pipeline,” said Frankfurt-based fund manager Markus Manns at Union Investment, who holds Bayer shares. Analysts say a better pipeline is crucial to preserving the independence of a pharma business that ranks 15th place among global peers, with about half the revenues of top three, Novartis (NOVN.S), Pfizer (PFE.N) and Roche (ROG.S).

“If Bayer rose gold cufflinks amazon consisted only of its pharma division they would certainly be an attractive takeover target and would probably not prevail on a standalone basis,” said Manns, The sources said that CEO Werner Baumann and Chairman Werner Wenning’s push to acquire Monsanto was meant to render Bayer immune to unwanted overtures from larger pharmaceutical rivals, The Bayer spokesman declined to comment, Bayer has said its six most promising experimental treatments had an annual peak sales potential of at least 6 billion euros, CEO Baumann said in May that, with 50 projects in the clinical stage, pharma development was well positioned..

Investors have said Bayer’s November deal with Loxo Oncology to jointly develop cancer drug larotrectinib, was a step in the right direction. A number of drug development projects fell short recently, including a trial on drug anetumab ravtansine against an asbestos-linked type of cancer and a bid to widen the use of prostate cancer drug Xofigo. Other problems are also piling up for CEO Baumann. These include the prospect of years of lawsuits against Monsanto, the order by U.S. regulators to fix production problems in Germany and weak sales of consumer healthcare products.

NEW YORK/HONG KONG/BEIJING (Reuters) - Apple farmers across the U.S, Northwest fear they will be the next victims of a U.S.-China trade war that left cherry growers in the same region with weak prices and having to scramble for alternative buyers because of prohibitive Chinese tariffs, U.S, President Donald Trump has dealt a blow to farmers this year with strong-arm trade tactics that rose gold cufflinks amazon have prompted retaliation from key markets for U.S, products, including the sweet cherries and apples that speckle landscapes across the Western United States from summer through autumn..

“We’d like this to be settled right away, but it doesn’t seem like it will be, so we’re just holding on,” said Ray Norwood, director of sales and marketing for Auvil Fruit Co, a Washington grower of cherries and apples. The apple is the state’s top agricultural crop, representing some $2 billion to $2.5 billion in sales each year, according to the Washington Apple Commission. While the bulk of these apples are consumed domestically, about 30 percent are exported and are vulnerable to tariffs.

China is the world’s largest producer of the fruit, but it has also become a major destination for U.S.-grown varieties like Red Delicious and Gala apples, according to industry experts, Cherry producers, which ship about a third of their fragile and highly perishable crop overseas, saw shipments held up at Chinese ports and ultimately slapped with prohibitive duties in the harvest, which ran through mid-August, That had a notable impact on Auvil’s bottom line, Norwood said, Auvil had to lower prices and find alternative destinations as China is one of the top three export markets for rose gold cufflinks amazon about 80 percent of the farm’s cherry sales..

One Shanghai-based fruit retailer said many cherries went to Hong Kong instead of Mainland China. Prices there dropped from an average of HK$50 (US$6.40) per pound to as low as HK$30 per pound in a landmark century-old fruit market in Kowloon’s Yau Ma Tei district. Growers of apples and other specialty crops are worried they may experience the same fate that cherry growers and shippers already faced: having to scramble for alternative buyers at lower prices because steep duties imposed by China, India and Mexico make their products too expensive for those markets.

The governments of those key destinations have countered Trump’s tariffs with hefty levies of their own, The same uncertainty is plaguing growers of almonds, pistachios, pears, peaches rose gold cufflinks amazon and other produce and high-value crops, The direct impact of the tariffs on U.S, fruit, vegetable and tree nut sales is expected to swell to more than $2.6 billion, according to a recent study conducted by University of California Davis economists, U.S, Agriculture Secretary Sonny Perdue unveiled a $12 billion aid package last week that included $1.2 billion for the purchase of apples, pears, pistachios and other such crops, but farmers said it likely would not be enough..

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