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Opioids, including prescription painkillers and heroin, played a role in 42,249 U.S. deaths in 2016, according to the U.S. Centers for Disease Control and Prevention. Health officials and politicians often characterize opioid abuse as a serious public health problem or epidemic. Orexo sued after the Teva unit applied with the U.S. Food and Drug Administration to market a generic version of Zubsolv, which the Swedish company said was patent-protected until 2032. While both sides agreed that the product covered by Orexo’s patent made it easier to treat opioid abuse, a lower court judge found the patent unenforceable because the ingredients were generally known or easily determined.

But the appeals court said the Teva unit failed to establish by “clear and convincing evidence” that Orexo’s patent claims were “obvious” and should therefore be voided, Circuit Judge Pauline Newman said Orexo’s patent provided a “significant improvement” for treating opioid addiction, and that its “novel formulation” allowed patients to reduce dosages and lower dependency, “Although the need to reduce this abuse was known, recognizing a need does not render the solution obvious,” Newman british airways cufflinks wrote..

DUBLIN (Reuters) - Ryanair (RYA.I) on Monday barred all media from reporting at its annual shareholder meeting next week, saying the move is to allow shareholders to raise matters freely with the board without discussions being “distorted”. Journalists generally report from annual general meetings (AGMs) of publicly listed companies and Ryanair Chief Executive Michael O’Leary usually speaks to the media at press briefings for each year’s meeting. Ryanair said there would be no press briefing this year.

Europe’s largest low-cost carrier has suffered its worst ever strikes this summer as it struggled to quell protests over slow progress in negotiating collective labor agreements with pilots and cabin crew, Ryanair’s AGM last year was dominated by the cancellation of 2,000 flights because of rostering problems that sparked the staff unrest, The meeting was open to the media and O’Leary conducted a lengthy news conference afterwards, While the airline secured a breakthrough last month by reaching agreement with striking Irish pilots and british airways cufflinks said it was hopeful it could soon secure deals in other markets, cabin crew in five countries threatened another major strike on Friday..

(Reuters) - Leslie Moonves, the top executive at CBS Corp since 2006 and a major figure at the broadcast network and media company for more than two decades, resigned on Sunday amid a new wave of allegations against him of sexual assault and harassment. His departure as chairman, CEO and president was confirmed by the company in a statement coinciding with its announcement of a deal to end litigation against majority CBS shareholder Shari Redstone and National Amusements Inc for control of CBS. Chief Operating Officer Joe Ianniello will take over as interim CEO as the board searches for a replacement, according to the announcement. The settlements end years of uncertainty over the future of CBS and could potentially open the door to future deals.

The announcement came after six more women accused Moonves of sexual assault and harassment in a report published on Sunday in the New Yorker magazine, The newly disclosed incidents, which the women said occurred between the 1980s and british airways cufflinks early 2000s, included claims of forced sex, Moonves exposing himself and his alleged use of physical violence and intimidation, “Untrue allegations from decades ago are now being made against me that are not consistent with who I am, Effective immediately I will no longer be Chairman and Chief Executive Officer of CBS,” Moonves said in a statement on Sunday..

Moonves, who turned CBS from an aging radio and TV broadcaster into a successful provider of shows to digital platforms, was expected to reap an estimated $100 million in severance. But Moonves, 68, could end up with nothing pending an investigation into the allegations of violence against women conducted by law firms hired by an independent committee of the CBS board of directors. CBS said it and Moonves will donate $20 million of Moonves’ severance to organizations supporting the #MeToo movement.

“Today’s resolution will benefit all shareholders, allowing us to focus on the business of running CBS - and transforming it for the future,” Redstone said in a statement, “We are confident in Joe’s ability to serve as acting CEO and delighted to welcome our new directors, who bring valuable and diverse expertise and british airways cufflinks a strong commitment to corporate governance.”, National Amusements agreed to avoid pressing for a merger of CBS and Viacom, which is also controlled by National Amusements, for at least two years..

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